- Comfort Inn & Suites Florence Center Area8.5Florence
- Econo Lodge Florence - Darlington5.1Florence
- Holiday Inn Express & Suites Florence by IHG8.3Florence
- La Quinta by Wyndham Florence7.4Florence
- SpringHill Suites Florence8.0Florence
- Red Roof Inn Florence - Civic Center6.0Florence
- Homewood Suites By Hilton Florence8.6Florence
- Landmark InnHartsville5.9
- The Mantissa Hotel8.6Hartsville
- Days Inn by Wyndham Florence Near Civic Center6.5Florence
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